First is that new mechanics, modes, formats, and card types can, at the very least, be finagled into MTG Arena
The Twisted Sewer-Witch brings you much closer to attacking for lethal, thanks to the wicked roles on your rats, even two other rats becoming 2/2s can make a big impact
Also, if you missed any of our past coverage of this count-up, feel free to read these articles below to refresh yourself
Alpha Deathclaw Angel of Despair Argentum Armor Assassin's Trophy Awaken the Maelstrom Bahamut, Warden of Light Beast Within Beast Within Clay Golem Combustion Man Desert Twister Despotic Scepter Generous Gift Giant Mana Cake Goblin Firebomb Hydroblast Jalum Grifter Karmic Justice Lexivore Lux Cannon Meteor Sword Necrotic Sliver Pentarch Paladin Pyroblast Ragnarok, Divine Deliverance Reaper King Rise of the Eldrazi Spine of Ish Sah Staff of Compleation The Most Dangerous Gamer Tornado Ugin, the Ineffable Ulamog, the Infinite Gyre Universal Solvent Unstable Obelisk Vindicate Wild Magic Surge