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Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4) Size:50mg 362 SMILES CC(C)(C)OC(=O)CCOCCN1CCNCC1 Purity (HPLC)

SKU: 10870035511

4.1
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Description

362 SMILES CC(C)(C)OC(=O)CCOCCN1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

This makes it ideal for high-resolution imaging techniques like STED (Stimulated Emission Depletion) and SIM (Structured Illumination Microscopy)

338 SMILES OC(=O)CCC(=O)NC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

SHP099 is a highly potent (IC50 = 0

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4) Size:50mg 362 SMILES CC(C)(C)OC(=O)CCOCCN1CCNCC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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