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Bioconjugate Chemistry
Product Name Thalidomide-O-acetamido-C3-azide Synonyms Thalidomide-4'-O-acetamido-C3-azide CAS Number n/a Related CAS Molecular Formula C18H18N6O6 Molecular Weight 414
164 Purity (HPLC) >= 95% Solubility DMSO
which readily reacts with an alkyne via click chemistry
Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae Bioconjugate ChemistrySOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker
