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HaXS8 Size:100nmol Product Name Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS

SKU: 17877589355

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Description

Product Name Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C83H136N12O23 Molecular Weight 1670

Product Name DOTA-PEG2-C2-amine Synonyms CAS Number 2866181-83-9 Related CAS Molecular Formula C22H42N6O9 Molecular Weight 534

S)-AHPC-CO-C6-NH2 HCl Synonyms CAS Number 2360522-76-3 Related CAS 2306389-03-5 (free base)

443 SMILES CC(C)(C)OC(=O)CN1CCN(CC2CCNCC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

HaXS8 Size:100nmol Product Name Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CASHaXS8 is a synthetic chemical dimerizer designed to induce covalent and irreversible intracellular dimerization between proteins tagged with HaloTag and SNAP tag. Its a bifunctional molecule featuring a chloroalkane group (specific for HaloTag) and an O6 benzylguanine (BG) derivative (specific for SNAP tag), connected by a flexible polyethylene glycol (PEG) linker. When introduced to cells, HaXS8 bridges HaloTag and SNAP tag fusion proteins by

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