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Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name Thalidomide-O-PEG3-C2-azide Synonyms Thalidomide-4'-O-PEG3-C2-azide

SKU: 23995909633

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Description

Product Name Thalidomide-O-PEG3-C2-azide Synonyms Thalidomide-4'-O-PEG3-C2-azide CAS Number 2758432-01-6 Related CAS Molecular Formula C21H25N5O8 Molecular Weight 475

Product Name Sulfo-CA-Lissamine Rhodamine B Synonyms Lissamine Rhodamine B Halotag Ligand Impermeable CAS Number N/A Related CAS N/A Molecular Formula C40H55ClN3O11S3 Molecular Weight 885

TCO (trans-cyclooctene) is a strained alkene used in click chemistry for bioorthogonal reactions like iEDDA (inverse electron-demand Diels-Alder)

Pure 5-isomer

Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name Thalidomide-O-PEG3-C2-azide Synonyms Thalidomide-4'-O-PEG3-C2-azideSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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