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DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB dbco-hexanoyl Nature Chem 5

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Description

Nature Chem 5

Reference:

Product Name DOTA-tris(t-Bu)ester-PEG2 Synonyms CAS Number n/a Related CAS Molecular Formula C32H61N5O9 Molecular Weight 659

SiR650 Acid CAS Number 1426090-03-0 Related CAS N/A Molecular Formula C27H28N2O4Si Molecular Weight 472

DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB dbco-hexanoyl Nature Chem 5SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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