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Ready for conjugation to a target protein ligand to form PROTACs containing Lenalidomide as cereblon ligand
the chloro atom in Biotin-PEG4-halo is replaced with a methyl group
34 SMILES OC(=O)C(F)(F)F
Product Name DOTA-tris(t-Bu)ester-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C36H68N8O10 Molecular Weight 772
Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-PNP snap Ready for conjugation to aSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating
