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Hormone Receptor-Positive
Product Name: 5(6)-FAM PEG3 azide Synonyms: 5-(and 6)-Carboxyfluorescein-PEG3-Azide CAS Number: N/A Molecular Formula: C29H28N4O9 Molecular Weight: 576
5-ROX is the purified single isomer of 5(6)-ROX
S)-AHPC-CO-C5-acid Synonyms CAS Number 2162120-87-6 Related CAS Molecular Formula C29H40N4O6S Molecular Weight 572
Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Hormone Receptor-PositiveSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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