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gov/ct2/show/NCT04191499 (accessed Mar 29
a reaction where tetrazine compounds react with strained dienophiles
Product Name Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C55H84N6O22 Molecular Weight 1181
Product Name Trametinib Synonyms CAS Number 871700-17-3 Related CAS Molecular Formula C26H23FIN5O4 Molecular Weight 615
Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) crbn gov/ct2/show/NCT04191499 (accessed Mar 29SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
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