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CP-CPY pab-mpeg Achieving In Vivo Target Depletion

SKU: 36106537332

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Description

Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders

Product Name Pomalidomide-5'-PEG1-C2-amine HCl Synonyms CAS Number n/a Related CAS 2412056-16-5 (free base) Molecular Formula C17H21ClN4O5 Molecular Weight 396

Isoindole-

a Azide-Dap(m-PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility

CP-CPY pab-mpeg Achieving In Vivo Target DepletionSNAP tag is a self labeling protein derived from human O6 alkylguanine DNA alkyltransferase. At 20 kDa, SNAP tag is smaller than HaloTag (33 kDa), potentially reducing interference with the tagged proteins function. SNAP tag reacts with covalently with benzylguanine (BG)or chloropyrimidine (CP) derivatives, forming a stable thioether bonds that ensures durability for long term experiments or harsh conditions. SNAP tag can be used alongside other tags

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