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Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan Size:5mg 189 Purity (HPLC) >= 95%

SKU: 44248023567

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Description

189 Purity (HPLC) >= 95% Solubility DMSO

942 Purity (HPLC) >= 95% Solubility DMSO

Product Name Thalidomide-5'-O-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C21H25N5O8 Molecular Weight 475

956 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan Size:5mg 189 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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