Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE m-peg4-pab 611 SMILES NCCOCCOCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC)

611 SMILES NCCOCCOCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

178 Purity (HPLC) >= 95% Solubility DMSO

aminopentyl)

69 SMILES [2H]C([2H])([2H])N(C1=CC=C(C)C=C1Cl)C([2H])([2H])[2H] Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE m-peg4-pab 611 SMILES NCCOCCOCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase