DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-PNP Size:100mg 362 SMILES OCCCCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

362 SMILES OCCCCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

1039/d3md00569k

enabling efficient and selective conjugation of the payload to the linker

6-SiR-CA CAS Number Related CAS Molecular Formula C37H48ClN3O5Si Molecular Weight 678

DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-PNP Size:100mg 362 SMILES OCCCCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine