CA-PhN3 deuterium-labeled-ketone 37 SMILES CC1=CC=C(NS(=O)(=O)C2=CC(=CC=C2)C#N)C2=C1C(=CN2)C#N Purity (HPLC)

37 SMILES CC1=CC=C(NS(=O)(=O)C2=CC(=CC=C2)C#N)C2=C1C(=CN2)C#N Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

AggFluors are quenched and remain non-fluorescent

Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody-drug conjugates

Product Name CC-220 Synonyms Iberdomide CAS Number 1323403-33-3 Related CAS Molecular Formula C25H27N3O5 Molecular Weight 449

CA-PhN3 deuterium-labeled-ketone 37 SMILES CC1=CC=C(NS(=O)(=O)C2=CC(=CC=C2)C#N)C2=C1C(=CN2)C#N Purity (HPLC)HaloTag is a self labeling protein tag engineered from the haloalkane dehalogenase DhaA, originally isolated from Rhodococcus rhodochrous. Its active site binds chloroalkane (CA)substrates, forming an irreversible covalent bond. This stable linkage between the HaloTag protein and its ligand enables rapid and efficient isolation and purification of tagged proteins. CA PhN3 is a HaloTag ligand containing an azide functional group, which readily reacts