Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-PNP Size:100mg Product Name DOTA-tris(t-Bu)ester-C6-amine Synonyms CAS

Product Name DOTA-tris(t-Bu)ester-C6-amine Synonyms CAS Number n/a Related CAS Molecular Formula C34H66N6O7 Molecular Weight 670

109 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C58H87N7O24 Molecular Weight 1266

07 SMILES CC(C)C(N(CCCN)C(=O)C1=CC=C(C)C=C1)C1=NC2=CC(Cl)=CC=C2C(=O)N1CC1=CC=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-PNP Size:100mg Product Name DOTA-tris(t-Bu)ester-C6-amine Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating