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DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Size:100mg Product Name tert-butyl 2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}acetate Synonyms

SKU: 79552868223

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Description

Product Name tert-butyl 2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}acetate Synonyms CAS Number 1181972-47-3 Related CAS Molecular Formula C14H29N3O3 Molecular Weight 287

650Ex/670Em) is a sulfonated derivative of its parent dye

943 Purity (HPLC) >= 95% Solubility DMSO

Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation

DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Size:100mg Product Name tert-butyl 2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}acetate SynonymsSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to

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