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Product Name DOTA-tris(t-Bu)ester-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C36H68N8O10 Molecular Weight 772
69 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader
Product Name Pomalidomide-CO-PEG5-C2-Cl Synonyms Pomalidomide-4'-CO-PEG5-C2-Cl CAS Number n/a Related CAS Molecular Formula C26H34ClN3O10 Molecular Weight 584
Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan aniline Product Name DOTA-tris(t-Bu)ester-PEG3-C2-azide Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage
