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Product Name ispinesib Synonyms 8F20
Product Name 5-FAM PEG3 alkyne Synonyms CAS Number N/A Related CAS Molecular Formula C30H27NO9 Molecular Weight 545
S)-AHPC-acetamido-O-PEG3-propargyl Synonyms CAS Number 2098799-81-4 Related CAS Molecular Formula C33H46N4O8S Molecular Weight 658
Product Name Thalidomide-5'-O-PEG2-C2-acid Synonyms CAS Number 2682112-08-7 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434
DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg Product Name ispinesib Synonyms 8F20SOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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