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Product Name DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C83H102FN9O20 Molecular Weight 1564
the labeling efficiency of tetramethylrhodamine maleimides and iodoacetamides is often lower compared to that of other tetramethylrhodamine labeling dyes
CA-SulfoCy5 is a HaloTag ligand with SulfoCyanine5 dye
Product Name Thalidomide-5'-alkyne-C4-OH Synonyms CAS Number n/a Related CAS Molecular Formula C19H18N2O5 Molecular Weight 354
Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan deuterium-labeled-ketone Product Name DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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