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This isnt absolutely necessary, but having a commander that can draw you some extra cards at any point during the game will make sure you never run out of things to do

For only two mana, Baral discounts the cost of instant and sorcery spells you control by one mana, allowing you to take control of a Commander pod

While there are plenty of other key reprints, such as Sorin, Imperious Bloodlord (for Rakdos Vampires in Pioneer), Bloodline Keeper only has 1 small reprint in the From the Vault: Transform

If an opponent destroys the creature youre targeting before your mutate effect resolves, then the creature you cast in mutate mode simply enters the battlefield as itself