Human FcRn GST Amount:250 µg Loetscher H

Loetscher H

Consistent with the inhibitory notion

overexpression of TRAIL-R3 prevents TRAIL-sensitive cells from apoptosis and cells can be re-sensitized by phospholipase treatment –consistent with the notion that TRAIL-R3 is GPI-anchored

Najakshin AM

Human FcRn GST Amount:250 µg Loetscher HHuman neonatal Fc receptor (FcRn) was named for its role in transferring IgG molecules across placenta to the fetus. Structurally, it is distinct from the classical IgG receptors for its similarity to the MHC class I instead of the Ig superfamily (IgSF) molecules. Binding of FcRn to IgG protects the latter from being proteolytically attacked by the endocytic lysosomal enzymes. The preservation of the antibody molecules by FcRn is central to the